Abstract: The optimal management of Cleft palate patient from birth to completion of the treatment continue to present a formidable challenge the professionals of the multidisciplinary cleft clinic (MDCC) specially children with Pierre Robin Sequence (PRS) than the children with Isolated cleft palate (ICP). The children with PRS have more challenge to develop normal articulation of consonants (Speech sounds except vowels) than ICP due to they are associated with congenital sequence of multiple anomalies, which cause to occur delayed surgery procedures.