Abstract: Wind and rain are climate hazards that threaten crops in agriculture. They contribute to crop yield losses in some areas of the world. They belong to the category of climate hazards classified as climate extremes. Our study aimed to investigate the influence of these two climatic threats on the cultivation of pawpaw (Carica papaya) in Meyomessala, South Cameroon. After three months of observation of 120 pawpaw plants sown in intercropping the first year and then in monoculture the second year; we used the Zephyr application and Daily Weather version 59 to measure wind and rainfall. The method for calculating vulnerability by weighting and Spearmans coefficient were used for statistical processing of the data.