Abstract: A field experiment was carried out during 2010/2011and 2011/2012 years to determine the extent of contamination of vegetables by tannery effluent in Ejersa area of East Shoa, Ethiopia. Five treatments comprised of tannery effluent of different concentrations levels, i.e., 0,25,50,75,100% applied to six vegetable plants like onion (Allium cepa L.), carrot (Daucus carota L.), beet root (Beta vulgaris L.), Swiss chard (Beta vulgaris L.), tomato (Lycopersicum esculentum L.) and cabbage (Brassica oleracea L.). The treatments were arranged in Randomized Complete Block Design (RCBD) with five effluent concentrations (treatments), each replicated three times. All vegetable plants grown with different effluent concentrations and the effects of different concentrations of effluents were compared to that of normal water (control). Parameters considered to study were heavy metals like (cadmium, chromium, copper, lead, iron, zinc).