Abstract: One of the reasons of low life expectancy in North East India is the large number of premature deaths of the infants, child and adults. Along with the decline in infant and child mortality rates, the focus now has to be on reducing the premature adult deaths. For that, analysis of the adult deaths and its causes that account for these deaths is very important. One of the important causes of such deaths is the diseases related to the circulatory system. This paper, therefore, attempts to focus on the diseases of circulatory system as one of the important causes of deaths, as provided by the data in the MCCD 2015, in the eight states of North Eastern Region of India. The paper also examines the age and sex variation in this cause-group of the deaths in the selected states.