Abstract: Background: To determine the factors relevant in understanding the behavior, perceptions and practices as well as religious attitude regarding organ donation of Moros residing in Davao City, Philippines.Material/Methods: A self-administered questionnaire was conducted between August to September 2017. A total of 469 questionnaires were distributed to different public communities and private institutions. 369 surveys were collected successfully and used for analysis. Results:Two most important independent variables as independent indicators of organ donation approval included high level of Islamic ethical principles and lesser score on Punishment of Allah appraisal