Abstract: Introduction: The aim of this present study was to determine the prevalence of early neonatal death at Gitwe hospital and identify associated factors. Objectives: The present study had the main purpose to determine the prevalence of early neonatal deaths at Gitwe Hospital and to describe early neonatal deaths and identify associated factors. Methods: The Retrospective present study was conducted using quantitative during a three years’ period whereby 92 cases includes only early neonatal mortality cases that occurred at Gitwe Hospital from 1st January 2008 to 31st December 2010 (3 years) were selected and interviewed.